Service
LiquidSCAN
LiquidSCAN is an NGS-based liquid biopsy solution that provides genome mutation information via liquid biopsy.
Analysis sensitivity and specificity have been improved through optimization of in-house library production development and application of a mutation detection algorithm in order to overcome the technological limits of conventional liquid biopsy. Repetitive non-invasive testing is possible and results of initial cancer diagnosis and therapeutic agent selection etc. are provided via analysis of the patient’s cancer genome. Currently, this is being provided as a research service and clinical trials are in progress for acquisition of approval by the Ministry of Food & Drug Safety. In addition, this can be provided through integration with tissue biopsy (CancerSCAN) via OncoSTATION, which is an automatic experiment and analysis data quality management system (LIMS).
Service order process
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01 Selection of analysis service and consultation -
02 Sample preparation -
03 Sample delivery
Sample analysis process
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01 Blood sample collection -
02 DNA extraction -
03 Library Prep -
04 Sequencing -
05 Data analysis -
06 Results report
Specification
-
01
Provision of accurate analysis
results by removing errors through
use of independently developed algorithm
-
02
Panel customizing for
the customer’s needs -
03
Provision of consultations, etc.
necessary for analysis
Analytic Performance Evaluation Results
| Categories | Detected Mutations | Non-Detected Mutations | Sensitivity | CI (95%) | Specificity | CI (95%) |
|---|---|---|---|---|---|---|
| SNV (>0.5%) | 79/81 | 2/81 | 98% | 91% - 100% | 99.9% | 99.9% - 100% |
| INDEL (>0.5%) | 53/54 | 1/54 | 98% | 90%-100% | 99.9% | 99.9% - 100% |
| CNV (>10%) | 27/27 | 0/27 | 100% | 87% - 100% | 100% | 93.4% - 100% |
| Fusion (>0.5%) | 51/54 | 3/54 | 94% | 85% - 99% | 99.9% | 99.8% - 100% |
| Total | 210/216 | 6/216 | 97% | 94% - 99% | 99.9% | 99.9% - 100% |
Service Types
| Service | Cancer type | Number of genes | |
|---|---|---|---|
| 1 | LiquidSCAN Compact | Pan-cancer | 44 |
| 2 | LiquidSCAN IO+ | Pan-cancer | 243 |
| 3 | LiquidSCAN Prostate | Prostate | 59 |
| 4 | LiquidSCAN Lymphoma | Lymphoma | 54 |
| 5 | LiquidSCAN RCC | Renal cell carcinoma | 51 |
| 6 | LiquidSCAN Follicular Lymphoma | Lymphoma | 58 |
Patents and Publications / Certifications
- Patents More than 12
- Publications More than 7
